Biotechnology - Domuspharma

Nutraceuticals have two big qualities: efficiency and security. At the same time, it is necessary to say that some of active natural substances, if used by humans in a natural way, have scarce probability to be assimilated. So these active substances are not completely effective. But if these molecules are supported by biological technologies, that do not change their structure, it is possible to have really effective active substances. Domuspharma has developed and patented these biotechnologies, using them for their products.

ARAR ® technique

The ARAR ® technique was patented in 2010: it is a method of microencapsulation, with periodically programmed time of release (8 hours). In this way, active substances microencapsulated by the Arar ® technique, are constantly delivered to a human body, all day long. Microencapsulation, using these natural materials, enables priobiotics to resist stomach acids, by protecting them during gastric and duodenal transit. So probiotics get to the intestinal wall (their final step) and can carry out the activity they are supposed to do. The Arar ® technique is also used for natural and chemical active substances different from probiotics. In particular, Domuspharma uses this technique for Probiogen product.
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Chitosan complex

Chitosan is a polymer of natural origin, derived by alkaline deacetylation of the chitin, present in exoskeleton of crustaceans, bugs and mushroom. The chitosan can be used in different fields, above all in pharmaceutical field thanks to his quality like biocompatibility, biodegradability and no toxicity. Furthermore, chitosan provides to help the drug paracellular transit. Recently, chitosan was also used to release drugs in a controlled way through mucous membrane, increasing the final bioavailability of active substances.

Domuspharma uses this biotechnology for Treacor product: Berberin-CH, Berberina complexed in chitosan microspheres (Drug dev Ind Pharm.2012Jan:38:104-10 doi:10.3109/03639045.2011.592531.Epub2001Jul20.): and for Biot product: Glucosamine-CH.
>> go to product page (Treacor);
>> go to product page (Biost).


Omevit is a nutraceutical composed by Omega-3 made up of high dosage of micro encapsulated EPA, DHA low dosage calibrated in FFA to increase 13,5 times plasmatic concentration, and deodorized through a multiple molecular distillation. This allows to decrease 80% of odors and to improve a patient’s compliance. Omevit was created with this specific skills to be aggressive against strict hypertriglyceridemia.
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Trealosio is a disaccharide, an inert sugar. It complexes and chelates the components inside it, improving bioavailability and lactobacilli accession on the intestinal wall, thanks to a truly important affinity for intestinal mucous membrane. (American molecular journal. Jul.,2011(1) - Ann Agric Environ Med. 2011 mar 23:19(1):99-102). Trealosio is present in Probiogen, Istamin Plus, Colis and Referol.
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